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KMID : 0616120060370040241
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Korean Journal of Pharmacognosy
2006 Volume.37 No. 4 p.241 ~ p.245
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Standardization of Morinda officinalis How
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Lee Hye-Won
Park So-young
Choo Byung-kil
Chun Jin-Mi
Lee A-Yeong
Kim Ho-kyoung
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Abstract
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Morinda officinalis How.(Rubiaceae) has been used as tonic, warming sex impulse and anti-inflammatory agents. Two known anthraquinones, rubiadin-1-methyl ether(Ⅰ) and rubiadin(Ⅱ) were isolated from root of M. officinalis. There structures were identified using NMR and literature comparisons. The contents of Ⅰ in eighteen M. officinalis were evaluated by HPLC-PDA. Chromatography was performed using a reversed-phase system with Luna C18(2) column and acetonitrile-water (50:50, v/v) with a flow rate of 1.0mL/min under UV 280nm. Under these comditions, the content of rubiadin-1-methyl ether was 0.013%.
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KEYWORD
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Morinda officinalis How, rubiadin, rubiadin-1-methyl ether, HPLC-PDA
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